Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Irritable bowel syndrome__20002-both_sexes-1154 |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_pos |
| GeneSet | CL23065, IONOTROPIC GLUTAMATE RECEPTOR, AND NEUROTRANSMITTER RECEPTOR TRANSPORT, POSTSYNAPTIC ENDOSOME TO LYSOSOME |
| Enrichment Score (ES) | 0.5945072 |
| Normalized Enrichment Score (NES) | 1.1973375 |
| Nominal p-value | 0.1891348 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.993 |
| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | GRIN2C | 1495 | 1.066 | 0.0843 | Yes |
| 2 | GRIN1 | 1551 | 1.048 | 0.2459 | Yes |
| 3 | GRIN2A | 1565 | 1.043 | 0.4090 | Yes |
| 4 | GRIA2 | 2379 | 0.823 | 0.4930 | Yes |
| 5 | GRIN2D | 3166 | 0.673 | 0.5550 | Yes |
| 6 | GRIA4 | 4825 | 0.470 | 0.5365 | Yes |
| 7 | GRIA1 | 5055 | 0.450 | 0.5945 | Yes |
| 8 | CACNG5 | 8816 | 0.228 | 0.4209 | No |
| 9 | CACNG8 | 10756 | 0.160 | 0.3381 | No |
| 10 | GRIN3B | 11937 | 0.129 | 0.2927 | No |
| 11 | CNIH3 | 13867 | 0.087 | 0.1990 | No |
| 12 | GRIN3A | 14107 | 0.083 | 0.1987 | No |
| 13 | CNIH2 | 15700 | 0.054 | 0.1185 | No |
| 14 | SHISA9 | 15849 | 0.051 | 0.1182 | No |
| 15 | CACNG2 | 17394 | -0.000 | 0.0322 | No |
| 16 | GRIN2B | 17944 | -0.000 | 0.0017 | No |
